Louisiana Museum, about 45 minutes by train from Copenhagen – would strongly recommend you visit if you are ever in the vicinity (that’s Sweden in the distance)
I have recently been in Copenhagen at the Euroanesthesia meeting. I went to an interesting talk on hypotension, where the speaker made a joke regarding people being tortured by the cerebral blood flow autoregulation curve in their primary exams. It seems a shame to limit the “torture” to the exam setting…..
I have posted on the effect of cerebral blood flow on ICP previously. You may find it useful to look at that post in conjunction with this one.
BT_RT 1.13 Describe the cerebral circulation, the regulation of cerebral blood flow and factors leading to the loss of autoregulation
The basics of this topic are covered in most physiology textbooks. However I think that Hemmings and Egan Ch 8 covers it better than most.
The first four statements cover important core material
Cerebral blood flow is autroregulated to maintain a constant flow in face of changing cerebral perfusion pressure T/F
Cerebral blood vessels are maximally dilated at the lower end of the autoregulation plateau T/F
As a general rule, the higher the cerebral metabolic rate, the higher the cerebral blood flow T/F
The most important factor in cerebral autoregulation is autonomic nervous system activity T/F
The speaker for the talk mentioned above was Adrian Gelb, from UCSF. Part of his talk referenced this article, which he authored, on the effect of CO2 on cerebral autoregulation. The article covers a lot of non core material, but I thought that his conceptualisation was very interesting, for those of you looking to explore the topic in more depth.
The last few T/F statements come from the article
Increased PaCO2 narrows the autoregulation range of blood pressures, by lowering the upper limit and elevating the lower limit T/F
The combination of hyopcapnoea and low normal BP may put the brain at risk of ischaemia T/F
The lower limit of autoregulation may be affected by the cause of the hypotension T/F