Agasgal has previously posted on these topics.
She also mentioned NAP6 https://www.nationalauditprojects.org.uk/NAP6home
The UK National Audit Projects have provided us with some invaluable information courtesy of their size and widespread buy in by the UK anaesthetic community. This is particularly helpful when you look at important adverse outcomes which are quite uncommon. NAP6 looked at perioperative anaphylaxis and the results came out earlier this year. If you don’t look at anything else look at the one page infographic summary. NAP7 will look at perioperative cardiac arrest. Our College’s ANZAAG have developed an online module which can be done to complete the anaphylaxis activity for the emergency CPD module.
Although NAP6 is undoubtedly important it hasn’t made its way to any of the textbooks yet- but it will. I am going to be proactive and ask a few questions relating to its findings as well as the content of the ANZAAG module.
T/F anaphylaxis is the leading cause of death directly related to anaesthesia
T/F the incidence of anaphylaxis in NAP6 was 1 in 10,000 anaesthetics
T/F the single worst offender for causing anaphylaxis in the UK was teicoplanin
T/F IM adrenaline should be administered as first line therapy for low grade anaphylaxis responses
T/F tryptases should be taken at 1, 2 and 4 hours post event.
T/F Noradrenaline, vasopressin and glucagon are recommended for use in refractory anaphylaxis
The top three causes of anaphylaxis in Australasia are antibiotics, muscle relaxants and what?