Insulin

BT_PO 1.90 Describe the pharmacology of insulin preparations …
BT_PO 1.85 Describe the control of blood glucose

T / F  the beta cells of the islets of Langerhans secrete proinsulin, which is then cleaved in the plasma to insulin

T / F  soluble insulin (Actrapid) starts working 30 minutes after S/C injection

T / F  insulin aspart (Novorapid) is more rapidly absorbed than Actrapid because it consists of only the A chain of amino acids

T / F  insulin glargine (Lantus) is slowly absorbed because the insulin is complexed with zinc and protamine

T / F  biguanides act by increasing cellular sensitivity to insulin

T / F  insulin increases the uptake of glucose into the liver, by upregulating the number of GLUT-4 transporters

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