Labour physiology and pharmacology

SB_OB 1.9 and SB_OB 1.8

Describe the influence of pregnancy on the pharmacokinetics and pharmacodynamics of drugs commonly used in anaesthesia and analgesia

Describe the anatomy and physiology of pain in labour and childbirth


Paracetamol is a category A drug in pregnancy, but care should still be taken in patients with pre-eclampsia. TRUE/FALSE

The addition of lipid-soluble opioids to lumbar epidurals allows a reduction of local anaesthetic concentration. TRUE/FALSE

Visceral pain receptors located in the lower uterine segment and cervix extend to the spinal segments of S2-S4. TRUE/FALSE

Oxygen consumption increases by 40% during the first stage of labour. TRUE/FALSE


Entonox side effects include maternal sedation. TRUE/FALSE.

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