BT_GS 1.12 Explain and describe clinical application of concepts relating to intravenous and infusion kinetics

The joys of pharmacokinetics are relatively few but a sound understanding of PK principles is a necessary evil for the anaesthetist. The following statements relate to the ubiquitous PK parameter, keo.

Q. Is the rate constant that describes transfer of drug from the central compartment to the effect site.  TRUE/ FALSE

Q. Is the rate constant for elimination of drug from the effect site.  TRUE/ FALSE

Q. Is directly proportional to the t1/2keo.  TRUE/ FALSE

Q. Can be measured directly using frequent blood sampling.  TRUE/ FALSE

Q. Has units of inverse time.  TRUE/ FALSE

 

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