BT_GS1.6 Describe the mechanisms of adverse drug reactions

Okay, BT_GS1.6 is not the most inspiring topic. There’s a neat ABCDEF classification in Hemmings and Egan that can give a skeleton for a SAQ or viva. Here’s some choice cuts to put on those bones…

 

Pharmcogenetic variation in acetylator status is important for several anaesthetic drugs TRUE/FALSE

Anaphylaxis to neuromuscular blocking drugs is more common in females   TRUE/FALSE

Chlorhexidine may be associated with severe hypersensitivity reactions    TRUE/FALSE

Both sevoflurane and desflurane may trigger immune-mediated hepatic failure   TRUE/FALSE

Nitrous oxide directly inhibits the conversion of homocysterine to methionine   TRUE/FALSE

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