It’s such fun being able to use so many different routes to administer drugs in our jobs. So many doctors out there don’t get our opportunities.
BT_PM 1.15 Discuss the pharmacokinetic and clinical implications of different routes of administration for commonly used opioids, including the oral, transdermal, subcutaneous, intramuscular and intravenous routes, and with particular reference to fentanyl, morphine, methadone, tramadol and codeine
Fentanyl undergoes significant first pass pulmonary uptake and metabolism. TRUE/FALSE
The cytochrome P450 3A4 (CYP3A4) is predominantly responsible for the metabolism of Alfentanil. TRUE/FALSE
Alfentanil undergoes extensive hepatic metabolism that demonstrates extensive interindividual variability TRUE/FALSE
The bioavailability of sublingual buprenorphine is similar to that of parenteral buprenorphine TRUE/FALSE
Epidural fentanyl undergoes a biphasic absorption pattern TRUE/FALSE