SS_OB 1.13 Placental transfer of drugs

Other end of the age spectrum today..

SS_OB 1.13 Explain the factors that influence the transfer of drugs across the placenta

Ionised drugs are more likely to cross the placenta compared with non-ionised drugs T/F

Heparin is safe to use in pregnancy because its large molecular size prevents it crossing the placenta T/F

Weakly basic drugs, with a pKa less than 7.4, may become concentrated in the fetal compartment secondary to increased levels of ionisation T/F

The placenta is capable of metabolising some drugs presented to it T/F

For highly lipid soluble drugs, degree of protein binding is an important factor in the rate of placental drug transfer T/F

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