SS_OB 1.9 Describe the influence of pregnancy on the pharmacokinetics and pharmacodynamics of drugs commonly used in anaesthesia and analgesia
TRUE/FALSE In pregnancy the average gain of 8 litres of total body water significantly increases the volume of distribution of hydrophilic drugs.
TRUE/FALSE Foetal and placental tissues provide another compartment for drug distribution.
TRUE/FALSE Pseudocholinesterase activity is decreased in pregnancy causing prolongation of succinylcholine block.
TRUE/FALSE Pregnancy reduces MAC by 25-30%.
TRUE/FALSE Nociceptive response thresholds are elevated in pregnancy.