I wanted to get you thinking about dose-effect curves as they are popular ( and sometimes pesky) little things in the vivas.
Tomorrow I will set some graphs for you to draw.
BT_GS 1.3 Define and explain dose-effect relationships of drugs with reference to:· Graded and quantal response
· Therapeutic index
· Potency and efficacy
· Competitive and non-competitive antagonists
· Partial agonists, mixed agonist-antagonists and inverse agonists
· Additive and synergistic effects of drug combinations
A quantal dose-response curves has axes of dose and proportion of population responding ( or % responding) T/F
The sigmoid shape of a quantal dose-response curve is because it is an example of a cumulative frequency distribution T/F
Quantal dose response curves show a graded response in a population T/F
Drug potency can be assessed using quantal dose-response curves T/F
Muscle relaxant dosing, using 2xED95 is determined from the ED50 on a quantal dose-response curve, where the quantal response is 95% twitch height reduction T/F